We assessed the probability of having VP based on PI values in patients with a definite diagnosis of either VP or idiopathic Parkinson's disease (IPD). PI was determined in all patients admitted to Hospital Universitari i Politècnic La Fe due to parkinsonism between January 2012 and June 2016. We aimed to confirm this association and to determine the PI value with the highest sensitivity and specificity for diagnosis of VP. An increase in transcranial Doppler ultrasonography pulsatility index (PI) has been described as a frequent finding in patients with VP.
#Vezer twtich series#
The diagnosis of vascular parkinsonism (VP) is based on a series of clinical criteria and neuroimaging findings. Increased pulsatility index supports diagnosis of vascular parkinsonism versus idiopathic Parkinson's disease.Ĭaba, L M Ferrairó, J I T Torres, I M Costa, J F V Muñoz, R B Martin, A L They infer that the usual rate of lossmore » of integrity of the dopaminergic nigrostriatal pathway in patients with idiopathic parkinsonism is slow and the rate of change between the two groups was comparable.« less The rate of decrease was almost identical in each group (p = 0.6). Both groups showed statistically significant reductions of striatal uptake over the interval.
The scans were analyzed by calculating the ratio of striatal to background radioactivity. The mean interval between the scans was 3.3 years for the group with idiopathic parkinsonism and 3.9 years for the control subjects. The authors performed sequential positron emission tomography scans with 6-(18F)fluoro-L-dopa in 9 patients with idiopathic parkinsonism and 7 age-matched normal control subjects to compare changes in the nigrostriatal dopaminergic pathway over time. Positron emission tomography suggests that the rate of progression of idiopathic parkinsonism is slow Predisposition arises from bereavement and/or maternal failure in early emotional development. A view of the condition is offered as a manifestation of chronic emotional disorder in an organic sense. The link between idiopathic Parkinson's disease and depression is examined in the light of psychosomatic theory. Idiopathic Parkinson's disease and depression: a psychosomatic view.
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